ea0045oc6.7 | Oral Communications 6- Endocrine | BSPED2016
Alatzoglou Kyriaki
, Gopalakrishnamoorthy Mahalakshmi
, Trewella Emily
, Mulla Aayesha
, Tan Hui-Leng
, Bridges Nicola
Background: Prader-Willi syndrome (PWS) is a complex genetic disorder caused by lack of expression of paternally inherited imprinted genes on Chr15q11-q13. rhGH has beneficial effects on growth, body composition and development. Starting age, dose titration and monitoring remain controversial.Objective: To study retrospectively children who presented in our multidisciplinary PWS clinic and assess response to rhGH treatment in terms of auxology, IGF1 conc...